Introduction: Triple-negative breast cancer (TNBC) is featured with the biological properties of strong aggressive behaviors, rapid disease progression, high risk of recurrence and metastasis, and low disease free survival. Palliative Therapy for Metastatic Breast Cancer Using PERTuzumab, Trastuzumab (HERCEPTIN), and DOCEtaxel as First-Line Treatment for Advanced Breast Cancer. Most metastatic breast cancers are breast cancer cells that remained in the body after treatment for early breast cancer. Bardia A et al. We recently spoke with Naoto T. Ueno, M.D., Ph.D. , section chief of Translational Breast Cancer Research in Breast Medical Oncology, to better understand TNBC. Chinese herbal medicine for oesophageal cancer. 2020 Dec 14;2020:8173147. doi: 10.1155/2020/8173147. For example, application of the PAM50 intrinsic subtype signature to subclassify the triple-negative breast cancer groups as basal-like and non-basal-like, or differentiated according to BRCA1 or BRCA2 status could be of benefit, to better identify the subpopulation of metastatic triple-negative breast cancer patients who might or might not benefit from the novel regimen. 4702-4710 .  |  Recent studies have shown promising activity of this regimen. This is a multicenter, prospective cohort study started in March 2016 in Beijing. Most cancers protocols nice to avoid consist of radiation, chemotherapy and mammograms. Please enable it to take advantage of the complete set of features! Doctors use the same tests and surgeries to figure out treatments for triple-negative breast cancers as they do for other kinds of breast cancer. Breast Cancer Res Treat. Introduction: Triple-negative breast cancer (TNBC) is featured with the biological properties of strong aggressive behaviors, rapid disease progression, high risk of recurrence and metastasis, and low disease free survival. Beyond single-agent chemotherapy, few effective treatment options are available for metastatic triple-negative breast cancer (TNBC), according to Candace Mainor, MD, but several approaches comprised of immunotherapy, antibody-drug conjugates (ADCs), and PARP inhibitors are shifting standards of care and eliciting impressive response rates in heavily pretreated patients. Clipboard, Search History, and several other advanced features are temporarily unavailable. Liu CT, Chen YH, Huang YC, Chen SY, Tsai MY. external icon; One is for the female hormone progesterone. Epub 2018 Jan 19. NIH Clin Res China 2012;25:417–9.23. The study has received ethical approval from the Research Ethical Committee of Beijing Hospital of Traditional Chinese Medicine affiliated to Capital Medical University (No.2016BL-014-01). 2018 Jun;97(24):e11064. Triple negative breast cancer treatment protocol - Breast cancer with HER2 excess can be treated with anti-HER2 drugs such as trastuzumab.  |  Abstract. ASCENT: A randomized phase 3 study of sacituzumab govitecan (SG) vs treatment of physician’s choice (TPC) in patients (pts) with previously treated metastatic triple-negative breast cancer (mTNBC). Altern Ther Health Med. INTRODUCTION TNBC accounts for 15–20% of all breast cancers and is typically associated with an aggressive disease course and a high risk for early recurrence and metastatic spread. Chinese Clinical Trial Registry: ChiCTR-OOC-16008246. Platinum chemotherapy is still controversial and currently not recommended as first-line treatment for TNBC. 2020. 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